1
Single injection at 3 mg/kg produced a statistically significant increase in total body lean mass and thigh muscle volume in healthy postmenopausal women.
View on PubMed →
ACE-031
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ACE-031 is a recombinant ActRIIB-Fc fusion protein that blocks myostatin, the body's primary brake on muscle growth. In a Phase I clinical trial, a single injection produced significant increases in lean body mass and thigh muscle volume. Phase II data in Duchenne muscular dystrophy showed trends for improved lean mass and bone density.
Every batch is independently tested by a 3rd party laboratory. Certificate of Analysis available below.
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Every batch is tested by an independent third-party laboratory with no commercial relationship to Camo Chem. We never self-certify. The full Certificate of Analysis is published on this page and verifiable directly with the testing lab.
Worldwide shipping. UK orders typically delivered in 1-3 working days. EU and international orders 3-7 working days. Tracked and signed-for delivery. Free shipping over £65 (UK) / €110 (EU) / $110 (US).
Store lyophilised powder in a cool, dry place away from direct light. After reconstitution with bacteriostatic water, refrigerate at 2-8°C.
Worldwide ShippingUK · EU · USA · Asia
3rd Party TestedIndependent lab CoA
≥98% HPLC PurityVerified per batch
Safe DeliveryDiscreet packaging
Research Overview
About this compound
What does the research say?
ACE-031 is an engineered protein designed as a "ligand trap" that intercepts myostatin and other members of the TGF-beta superfamily before they can bind to their cell-surface receptors. Myostatin is the body's primary brake on muscle growth. By blocking it, ACE-031 effectively removes that brake.
In a Phase I clinical study involving healthy postmenopausal women, a single injection of ACE-031 at 3 mg/kg produced a statistically significant increase in total body lean mass and thigh muscle volume. In a separate Phase II trial in boys with Duchenne muscular dystrophy, ACE-031 showed trends for increased lean body mass, increased bone mineral density, and reduced fat mass.
These are not marketing claims. These are peer-reviewed, published results. You can verify every reference below.
Why does quality matter with ACE-031?
ACE-031 is a complex recombinant fusion protein. Its activity depends on correct folding and the integrity of both the ActRIIB binding domain and the Fc region. Degraded or improperly produced material will not function as a myostatin trap.
At Camo Chem, every batch is tested by an independent 3rd party laboratory. We publish the full Certificate of Analysis for every batch, and you can verify the results directly with the lab. We do not self-certify. Ever.
Ask your current supplier: who tests their products?
Technical Data
Compound specifications
| Common Names | ACE-031, Ramatercept |
| CAS Number | 1621169-52-5 |
| Classification | ActRIIB-Fc fusion protein / Myostatin inhibitor |
| Purity | ≥98% (HPLC verified) |
| Content per Vial | 1 mg |
| Physical Form | Lyophilised (freeze-dried) white powder |
| Solubility | Soluble in water and bacteriostatic water |
| Storage | Powder: cool, dry place. After reconstitution: 2-8°C. |
Peer-reviewed Studies
Published research on ACE-031
2
Trends for increased lean body mass, bone mineral density, and reduced fat mass in boys with Duchenne muscular dystrophy.
View on PubMed →3
Preclinical data showed increased muscle fiber cross-sectional area in both type 1 and type 2 fibers in young mice.
View on PubMed →
Customer Reviews
What researchers are saying
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FAQ
Frequently asked questions
ACE-031 (Ramatercept) is a recombinant fusion protein consisting of the extracellular domain of human activin receptor type IIB (ActRIIB) fused to the Fc portion of human IgG1. It functions as a soluble decoy receptor that traps myostatin and other TGF-beta family ligands. Its CAS number is 1621169-52-5. It is sold exclusively as a research compound.
ACE-031 intercepts myostatin and related ligands (activin A, GDF-11) before they can bind to cell-surface receptors, effectively removing the biological brake on muscle growth. This is known as a "ligand trap" mechanism.
Every batch meets a minimum of 98% purity as verified by HPLC. Testing is performed by an independent 3rd party laboratory. The CoA is available on this page.
Yes. ACE-031 is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use.
In lyophilised form, store in a cool, dry place. After reconstitution, refrigerate at 2-8°C.
