Thymosin Beta-4 activated integrin-linked kinase and promoted cardiac cell migration, survival, and cardiac repair following ischaemic injury.
View on PubMed →
TB500
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TB-500 is a synthetic analogue of Thymosin Beta-4 (Tβ4), one of the most abundant intracellular peptides in mammalian tissues. It replicates the active actin-binding region responsible for cell migration and tissue repair. Published research in Nature demonstrated its role in cardiac cell survival and repair following ischaemic injury.
Every batch is independently tested by a 3rd party laboratory. Certificate of Analysis available below.
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Every batch is tested by an independent third-party laboratory with no commercial relationship to Camo Chem. We never self-certify. The full Certificate of Analysis is published on this page and verifiable directly with the testing lab.
Worldwide shipping. UK orders typically delivered in 1-3 working days. EU and international orders 3-7 working days. Tracked and signed-for delivery. Free shipping over £65 (UK) / €110 (EU) / $110 (US).
Store lyophilised powder in a cool, dry place away from direct light. After reconstitution with bacteriostatic water, refrigerate at 2-8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
About this compound
What does the research say?
TB-500 replicates the active actin-binding region of Thymosin Beta-4 (Tβ4), a 43-amino acid peptide present in virtually all human and animal cells. Its primary biological function is regulating actin polymerisation, which directly influences cell motility, migration, and tissue repair.
In preclinical models, TB-500 promoted new blood vessel formation, accelerated wound healing, and reduced pro-inflammatory cytokines. A landmark study published in Nature showed that Thymosin Beta-4 activated integrin-linked kinase and promoted cardiac cell migration, survival, and cardiac repair following ischaemic injury.
These are not marketing claims. These are peer-reviewed, published results. You can verify every reference below.
Why does quality matter with TB-500?
TB-500 is a complex peptide that requires precise synthesis. Its biological activity depends on correct folding of the actin-binding domain. Impurities or degradation products can interfere with this critical structure.
At Camo Chem, every batch is tested by an independent 3rd party laboratory. We publish the full Certificate of Analysis for every batch, and you can verify the results directly with the lab. We do not self-certify. Ever.
Ask your current supplier: who tests their products?
Compound specifications
| Common Names | TB-500, TB500, Thymosin Beta-4 Fragment |
| CAS Number | 77591-33-4 |
| Parent Compound | Thymosin Beta-4 (Tβ4) |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | ~4,963 g/mol |
| Classification | Actin-sequestering peptide / Tissue repair peptide |
| Purity | ≥98% (HPLC verified) |
| Content per Vial | 5 mg |
| Physical Form | Lyophilised (freeze-dried) white powder |
| Solubility | Soluble in water and bacteriostatic water |
| Storage | Powder: cool, dry place. After reconstitution: 2-8°C. |
Published research on TB-500
Promoted endothelial cell differentiation, angiogenesis, and accelerated wound healing in preclinical models.
View on PubMed →Reduced pro-inflammatory cytokines and modulated cardiac repair pathways in multiple in vivo models.
View on PubMed →What researchers are saying
definetely felt it helping me heal my injuries i had for months
Works well, speedy delivery
I wasn’t expecting to break through a plateau with this - my introduction to peptides was life changing. Safe, easy, fast delivery, very effective product. Will be ordering more and sticking with Chamo Chem from now on.
Good product, but expensive!
I like the product and the price is not great but ok especially for a tested quality. My only problem is that 2 vials had no vacuum in it and Im a bit worried that it was exposed or destroyed – maybe due to transport.
Frequently asked questions
TB-500 is a synthetic analogue of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide involved in actin regulation, cell migration, and tissue repair. Its CAS number is 77591-33-4. It is sold exclusively as a research compound.
Every batch meets a minimum of 98% purity as verified by HPLC. Testing is performed by an independent 3rd party laboratory. The CoA is available on this page.
By an independent laboratory with no commercial relationship with our company. We do not self-certify. Our CoAs are verifiable directly with the testing lab.
Yes. TB-500 is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use.
In lyophilised form, store in a cool, dry place. After reconstitution, refrigerate at 2-8°C and use within 28 days.