1
Increased running endurance by 44% in sedentary mice after 4 weeks without any exercise training.
View on PubMed →
AICAR EU
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AICAR (Acadesine) is a potent AMPK activator that mimics the metabolic effects of exercise. In a study published in Cell, AICAR increased running endurance by 44% in sedentary mice without any exercise training. It activates the same metabolic pathways as endurance training, shifting energy metabolism towards fatty acid oxidation.
Every batch is independently tested by a 3rd party laboratory. Certificate of Analysis available below.
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Every batch is tested by an independent third-party laboratory with no commercial relationship to Camo Chem. We never self-certify. The full Certificate of Analysis is published on this page and verifiable directly with the testing lab.
Worldwide shipping. UK orders typically delivered in 1-3 working days. EU and international orders 3-7 working days. Tracked and signed-for delivery. Free shipping over £65 (UK) / €110 (EU) / $110 (US).
Store lyophilised powder in a cool, dry place. After reconstitution, refrigerate at 2-8°C.
Don't forget
Bacteriostatic water
Required for reconstituting lyophilised peptides. European Warehouse.
Reconstitution
Need help with dosing?
Calculate the exact volume of bacteriostatic water for your target dose.
Worldwide ShippingUK · EU · USA · Asia
3rd Party TestedIndependent lab CoA
≥98% HPLC PurityVerified per batch
Safe DeliveryDiscreet packaging
Research Overview
About this compound
What does the research say?
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable nucleoside analogue that activates AMP-activated protein kinase (AMPK), the same master metabolic switch activated by exercise and caloric restriction. AMPK activation shifts cellular energy metabolism from anabolic to catabolic pathways, promoting fatty acid oxidation and glucose uptake.
In a landmark study published in Cell, AICAR administered to sedentary mice for 4 weeks increased running endurance by 44% without any exercise training. The compound activated a network of 32 genes associated with oxidative metabolism in muscle tissue, effectively mimicking the metabolic adaptations produced by endurance training. AICAR has also been studied for its cardioprotective effects during ischaemia-reperfusion injury.
These are not marketing claims. These are peer-reviewed, published results. You can verify every reference below.
Why does quality matter with AICAR?
AICAR is a nucleoside analogue that must be in the correct ribonucleotide form for intracellular conversion to ZMP, the actual AMPK activator. Impure or degraded material will not activate AMPK effectively.
At Camo Chem, every batch is tested by an independent 3rd party laboratory. We publish the full Certificate of Analysis for every batch, and you can verify the results directly with the lab. We do not self-certify. Ever.
Ask your current supplier: who tests their products?
Technical Data
Compound specifications
| Common Names | AICAR, Acadesine, AICA Ribonucleotide, ZMP precursor |
| CAS Number | 2627-69-2 |
| Molecular Formula | C₉H₁₄N₄O₅ |
| Molecular Weight | 258.23 g/mol |
| Classification | AMPK activator / Exercise mimetic |
| Purity | ≥98% (HPLC verified) |
| Content per Vial | 50 mg |
| Physical Form | Lyophilised (freeze-dried) white powder |
| Solubility | Soluble in water and bacteriostatic water |
| Storage | Powder: cool, dry place. After reconstitution: 2-8°C. |
Peer-reviewed Studies
Published research on AICAR
2
Activated a network of 32 genes associated with oxidative metabolism in muscle, mimicking endurance training adaptations.
View on PubMed →3
Demonstrated cardioprotective effects during ischaemia-reperfusion injury in preclinical models.
View on PubMed →
Customer Reviews
What researchers are saying
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FAQ
Frequently asked questions
AICAR (Acadesine) is a cell-permeable nucleoside analogue with CAS number 2627-69-2. It activates AMPK, the same metabolic master switch activated by exercise. It is sold exclusively as a research compound.
No. AICAR is a nucleoside analogue, not a peptide. It is categorised with peptides due to its research applications in metabolic and endurance studies.
Every batch meets a minimum of 98% purity as verified by HPLC. Testing is performed by an independent 3rd party laboratory.
Yes. AICAR is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water or sterile water before use.
In lyophilised form, store in a cool, dry place. After reconstitution, refrigerate at 2-8°C.
